| Date | Opponent | Result | 
|---|---|---|
| vs  MIA  | W 130-120 | |
| at  MEM  | W 112-117 | |
| at  MIN  | W 115-116 | |
| vs  POR  | L 108-122 | |
| at  SAC  | W 120-127 | 
| Date | Opponent | Result | 
|---|---|---|
| at  BKN  | W 105-129 | |
| vs  BOS  | L 108-109 | |
| at  WAS  | W 134-139 | |
| vs  ORL  | W 136-124 | |
| vs  CHA  | W 125-121 | 
| Player | Pos | Date | Injury | Status | 
|---|---|---|---|---|
| C | Back | Ayton did not play on Sunday's (Nov. 2) game against the Heat. | ||
| G | Ankle | The Los Angeles Lakers said on Monday (Oct. 27) that Vincent is expected to miss two to four weeks, per Shams Charania of ESPN. | ||
| F | Oblique | The Lakers announced Tuesday (Oct. 21) that Kleber will be re-evaluated in two weeks due to a left oblique strain, as per Mike Trudell of Spectrum SportsNet. | ||
| G | Knee | The Lakers said on Sunday (Oct. 19) that Thiero was a modified practice participant but he is not expected to be ready for the start of the regular season, per Khobi Price of The Orange County Register. | ||
| F | Nerve | James isn't expected to make his 2025-26 debut until around mid-November, as per Shams Charania of ESPN. | 
| Player | Pos | Date | Injury | Status | 
|---|---|---|---|---|
| C-F | Rest | Embiid did not play on Sunday's (Nov. 2) game against the Nets. | ||
| F | Elbow | Barlow did not play on Sunday's (Nov. 2) game against the Nets. | ||
| F | Knee | George did not play on Sunday's (Nov. 2) game against the Nets. | ||
| G | Thumb | The 76ers said on Wednesday (Oct. 15) that McCain's timeline for return to the floor is on Nov. 8. |